Jian Yan Selected Research

Inflammation (Inflammations)

1/2023	Stimulation of Liver Fibrosis by N2 Neutrophils in Wilson's Disease.
12/2022	Type 1 diabetes risk genes mediate pancreatic beta cell survival in response to proinflammatory cytokines.
1/2020	Increased estrogen levels altered microRNA expression in prostate and plasma of rats dosed with sex hormones.
2/2019	Maternal Choline Supplementation Modulates Placental Markers of Inflammation, Angiogenesis, and Apoptosis in a Mouse Model of Placental Insufficiency.
1/2017	Maternal choline supplementation during murine pregnancy modulates placental markers of inflammation, apoptosis and vascularization in a fetal sex-dependent manner.
8/2015	Cardioprotection by PI3K-mediated signaling is required for anti-arrhythmia and myocardial repair in response to ischemic preconditioning in infarcted pig hearts.
10/2013	[Activation of Kupffer cell and related signal pathway proteins in the liver of high fat and high fructose diet induced NAFLD mice].
9/2012	Intradermal DNA vaccination enhanced by low-current electroporation improves antigen expression and induces robust cellular and humoral immune responses.
6/2012	Optimization of electroporation-enhanced intradermal delivery of DNA vaccine using a minimally invasive surface device.
1/2012	MicroRNA expression profiles distinguish the carcinogenic effects of riddelliine in rat liver.

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Jian Yan Research Topics

Disease

43	Neoplasms (Cancer) 04/2024 - 01/2002
20	Infections 01/2021 - 04/2007
11	Human Influenza (Influenza) 01/2018 - 04/2007
10	Inflammation (Inflammations) 01/2023 - 01/2012
7	Carcinogenesis 01/2017 - 04/2003
6	Hepatocellular Carcinoma (Hepatoma) 04/2024 - 01/2012
5	Arthritis (Polyarthritis) 12/2023 - 04/2011
5	Prostatic Neoplasms (Prostate Cancer) 01/2022 - 02/2014
4	Communicable Diseases (Infectious Diseases) 01/2019 - 09/2012
3	Fibrosis (Cirrhosis) 01/2023 - 01/2016
3	Placental Insufficiency 10/2019 - 07/2017
3	Uterine Cervical Dysplasia 01/2018 - 10/2012
3	Hypoxia (Hypoxemia) 12/2017 - 01/2016
3	Liver Cirrhosis (Hepatic Cirrhosis) 08/2013 - 01/2012
3	Influenza in Birds (Avian Flu) 05/2009 - 04/2007
3	Phototoxic Dermatitis (Phototoxicity) 09/2005 - 08/2004
2	Subarachnoid Hemorrhage (Aneurysmal Subarachnoid Hemorrhage) 12/2023 - 12/2019
2	Heart Failure 12/2023 - 08/2015
2	Hepatolenticular Degeneration (Wilson's Disease) 01/2023 - 10/2020
2	COVID-19 12/2022 - 01/2020
2	Retinoblastoma (Glioblastoma, Retinal) 06/2022 - 04/2020
2	Erythema 01/2022 - 11/2015
2	Glioma (Gliomas) 01/2021 - 01/2019
2	Fever (Fevers) 01/2021 - 01/2015
2	Emerging Communicable Diseases (Emerging Infectious Diseases) 01/2021 - 05/2014
2	Lymphoma (Lymphomas) 01/2021 - 12/2018
2	Lung Neoplasms (Lung Cancer) 04/2020 - 04/2018
2	Carcinoma (Carcinomatosis) 12/2018 - 08/2013
2	Chronic Disease (Chronic Diseases) 01/2018 - 01/2017
2	Pain (Aches) 11/2017 - 10/2012
2	Obesity 10/2016 - 11/2015
2	Choline Deficiency 10/2016 - 05/2010
2	HIV Infections (HIV Infection) 03/2015 - 06/2012
2	Breast Neoplasms (Breast Cancer) 01/2015 - 08/2013
2	Body Weight (Weight, Body) 08/2014 - 01/2012
2	Scurvy (Scorbutus) 07/2011 - 01/2007
2	Hemangiosarcoma (Angiosarcoma) 04/2004 - 04/2003
1	Liver Neoplasms (Liver Cancer) 08/2023
1	Cholangiocarcinoma 05/2023
1	Lymphatic Metastasis 05/2023
1	Diabetic Retinopathy (Retinopathy, Diabetic) 02/2023
1	Vision Disorders (Hemeralopia) 02/2023
1	Hyperglycemia 02/2023
1	Pathologic Neovascularization 02/2023

Drug/Important Bio-Agent (IBA)

27	VaccinesIBA 04/2024 - 04/2007
20	DNA (Deoxyribonucleic Acid)IBA 01/2023 - 05/2008
18	DNA VaccinesIBA 12/2022 - 04/2007
16	AntigensIBA 01/2020 - 04/2007
11	Proteins (Proteins, Gene)FDA Link 02/2023 - 03/2013
9	Choline (Choline Chloride)IBA 10/2019 - 04/2010
8	Biomarkers (Surrogate Marker)IBA 01/2023 - 11/2015
8	MicroRNAs (MicroRNA)IBA 08/2020 - 01/2012
6	Monoclonal AntibodiesIBA 01/2019 - 08/2013
6	riddelliineIBA 01/2012 - 07/2002
5	Interleukin-1 Receptors (Interleukin 1 Receptor)IBA 12/2023 - 04/2011
5	CytokinesIBA 12/2022 - 02/2013
4	Transcription Factors (Transcription Factor)IBA 12/2022 - 07/2010
4	Long Noncoding RNAIBA 06/2022 - 01/2019
4	Neoplasm Antigens (Tumor Antigens)IBA 01/2020 - 08/2013
4	A-Form DNA (A-DNA)IBA 01/2020 - 04/2007
4	AntibodiesIBA 01/2020 - 09/2015
4	DNA AdductsIBA 05/2008 - 04/2003
3	Connexin 43 (Connexin43)IBA 12/2023 - 08/2015
3	Interleukin-6 (Interleukin 6)IBA 01/2022 - 01/2016
3	Messenger RNA (mRNA)IBA 04/2020 - 02/2014
3	CarcinogensIBA 01/2017 - 05/2015
3	InterferonsIBA 01/2016 - 10/2012
3	Pyrrolizidine AlkaloidsIBA 05/2008 - 04/2003
2	Immune Checkpoint InhibitorsIBA 04/2024 - 01/2018
2	Cancer VaccinesIBA 04/2024 - 01/2020
2	CollagenIBA 12/2023 - 08/2015
2	AlbuminsIBA 08/2023 - 01/2017
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 02/2023 - 06/2018
2	CopperIBA 01/2023 - 10/2020
2	reluscovtogene ralaplasmidIBA 12/2022 - 01/2020
2	ChromatinIBA 01/2019 - 02/2014
2	Glycoproteins (Glycoprotein)IBA 11/2018 - 05/2014
2	VGX-3100IBA 01/2018 - 11/2015
2	Influenza Vaccines (Influenza Vaccine)FDA Link 01/2018 - 01/2018
2	Hemagglutinins (Hemagglutinin)IBA 01/2018 - 05/2014
2	trimethyloxamine (trimethylamine N-oxide)IBA 01/2017 - 01/2017
2	Folic Acid (Vitamin M)FDA LinkGeneric 10/2016 - 11/2015
2	UbiquitinIBA 10/2015 - 05/2015
2	L-Gulonolactone OxidaseIBA 05/2013 - 07/2011
2	NucleoproteinsIBA 06/2012 - 09/2011
1	Programmed Cell Death 1 ReceptorIBA 04/2024
1	T-Cell Antigen Receptors (T-Cell Receptor)IBA 04/2024
1	Complementarity Determining Regions (Complementarity Determining Region)IBA 04/2024
1	pembrolizumabIBA 04/2024
1	LeptinIBA 12/2023
1	BilirubinIBA 08/2023
1	Cytidine Triphosphate (CTP)IBA 08/2023
1	Becaplermin (PDGF-BB)FDA Link 05/2023
1	Methanol (Carbinol)IBA 02/2023
1	2,5-dichloro-4-bromophenol (B 2)IBA 02/2023
1	ThioredoxinsIBA 02/2023
1	ZincIBA 01/2023

Therapy/Procedure

14	Therapeutics 10/2020 - 03/2013
7	Immunotherapy 01/2020 - 09/2008
2	Qigong (Qi Gong) 10/2018 - 01/2018